Author

A. W. Navia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. K. Shalek· 3 shared J. Ordovas-Montanes· 2 shared V. N. Miao· 2 shared A. A. Borah· 1 shared A. Bein· 1 shared A. D. Cherniack· 1 shared A. Dahal· 1 shared A. DenAdel· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBioengineering

A. K. Shalek

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enteric coronavirus infection and treatment modeled with an immunocompetent human intestine-on-a-chip

A. Bein, S. Kim, G. Goyal, W. Cao, C. Fadel, A. Naziripour, S. Sharma, B. Swenor, N. LoGrande, A. Nurani, V. N. Miao, A. W. Navia, C. G. Ziegler, J. Ordovas-Montanes, P. Prabhala, , D. E. Ingber

This paper uses an intestine-on-a-chip model to study NL63 coronavirus infection effects on the human intestine and tests antiviral treatments.

Frontiers in Pharmacology · Oct 25, 2021Peer-reviewedBioengineering

Microenvironmental correlates of immune checkpoint inhibitor response in human melanoma brain metastases revealed by T cell receptor and single-cell RNA sequencing

C. A. Alvarez-Breckenridge, S. C. Markson, J. H. Stocking, N. Nayyar, M. Lastrapes, M. R. Strickland, A. E. Kim, M. de Sauvage, A. Dahal, J. M. Larson, J. L. Mora, A. W. Navia, B. M. Kuter, C. M. Gill, M. S. Bertalan, , Bra

bioRxiv · Aug 25, 2021Cancer Biology

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

C. G. K. Ziegler, V. N. Miao, A. H. Owings, A. W. Navia, Y. Tang, J. D. Bromley, P. Lotfy, M. Sloan, H. Laird, H. B. Williams, M. George, R. S. Drake, T. Christian, A. Parker, C. B. Sindel, , J. Ordovas-Montanes

This study analyzes nasopharyngeal samples from COVID-19 patients and healthy controls to identify how SARS-CoV-2 infection affects respiratory epithelial cells and immune responses, finding impaired local intrinsic immunity in severe cases.

bioRxiv · Feb 20, 2021Immunology

The tumor microenvironment drives transcriptional phenotypes and their plasticity in metastatic pancreatic cancer

S. Raghavan, P. S. Winter, A. W. Navia, H. L. Williams, A. DenAdel, R. L. Kalekar, J. Galvez-Reyes, K. E. Lowder, N. Mulugeta, M. S. Raghavan, A. A. Borah, K. S. Kapner, S. A. Vayrynen, A. Dias Costa, R. W. S. Ng, , A. K. Shalek

This study identifies a transitional cancer cell state in metastatic pancreatic cancer and shows that tumor microenvironment signals drive transcriptional plasticity and subtype transitions.

bioRxiv · Aug 25, 2020 · PreprintCancer Biology