Author

C. GeurtsvanKessel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Koopmans· 4 shared B. Rockx· 3 shared M. M. Lamers· 3 shared B. Haagmans· 2 shared D. Noack· 2 shared D. van Riel· 2 shared M. Rissmann· 2 shared P. van Run· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

M. Koopmans

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4 papers

Recent·Most cited

Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters

M. Rissmann, D. Noack, D. van Riel, K. S. Schmitz, R. D. de Vries, P. van Run, M. M. Lamers, C. GeurtsvanKessel, M. Koopmans, R. Fouchier, T. Kuiken, B. Haagmans, B. Rockx

This study inoculates Syrian golden hamsters with SARS-CoV-2 Omicron BA.1 to compare its pathogenicity and viral shedding to Delta, finding reduced clinical signs and viral shedding but still pneumonia, with pre-existing immunity offering protection.

bioRxiv · Mar 15, 2022Microbiology

Omicron BA.1 and BA.2 are antigenically distinct SARS-CoV-2 variants

A. Z. Mykytyn, M. Rissmann, A. Kok, M. Rosu, D. Schipper, T. I. Breugem, P. B. van den Doel, F. Chandler, T. Bestebroer, M. de Wit, M. E. van Royen, R. Molenkamp, B. Oude Munnink, R. D. de Vries, C. GeurtsvanKessel, , B. Haagmans

This study compares the antigenic differences between SARS-CoV-2 Omicron BA.1 and BA.2 variants using antigenic cartography and hamster sera, finding they are distinct antigenic outliers.

bioRxiv · Feb 23, 2022 · PreprintMicrobiology

Temporal kinetics of RNAemia and associated systemic cytokines in hospitalized COVID-19 patients

D. van Riel, C. Embregts, G. J. Sips, J. van den Akker, H. Endeman, E. van Nood, J. J. van Kampen, R. Molenkamp, M. Koopmans, d. van de vijver, C. GeurtsvanKessel

This study examines the temporal changes in viral RNA and cytokine levels in hospitalized COVID-19 patients, finding differences in RNAemia duration and cytokine associations with disease severity.

bioRxiv · Dec 17, 2020Microbiology

SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model

B. L. Haagmans, D. Noack, N. M. A. Okba, W. LI, C. Wang, T. Bestebroer, R. de Vries, S. Herfst, D. de Meulder, P. van Run, M. M. Lamers, B. Rijnders, C. Rokx, F. J. M. van Kuppeveld, F. Grosveld, , B. Rockx

This study shows that high-dose convalescent plasma or monoclonal antibodies protect hamsters from SARS-CoV-2-induced lower respiratory disease, but lower doses are ineffective.

bioRxiv · Aug 24, 2020Microbiology