Author

R. de Vries

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. A. van Apeldoorn· 1 shared A. Goodson· 1 shared A. Hernandez Garcia· 1 shared A. K. Bera· 1 shared A. Kang· 1 shared A. Stell· 1 shared A. van Apeldoorn· 1 shared B. J. Bosch· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperCell Biology

A. A. van Apeldoorn

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Author profile →

6 papers

Recent·Most cited

Curvature-induced lipid sorting beyond the critical packing parameter

M. Konig, R. de Vries, F. Grunewald, S.-J. Marrink, W. Pezeshkian

This study uses molecular dynamics simulations to show that membrane curvature affects lipid sorting and phase behavior in complex ways beyond traditional models.

bioRxiv · Dec 15, 2023 · PreprintBiophysics

Rapid and automated design of two-component protein nanomaterials using ProteinMPNN

R. J. de Haas, N. Brunette, A. Goodson, J. Dauparas, S. Y. Yi, E. C. Yang, Q. Dowling, H. Nguyen, A. Kang, A. K. Bera, B. Sankaran, R. de Vries, D. Baker, N. P. King

This study benchmarks ProteinMPNN against Rosetta in designing two-component protein nanomaterials, showing comparable success with significantly reduced computation and no manual refinement.

bioRxiv · Aug 4, 2023Biochemistry

Adipose-derived stromal cells preserve pancreatic islet function in a transplantable 3D bioprinted scaffold

S. Abadpour, E. M. Niemi, L. S. Orrhult, C. Hermanns, R. de Vries, L. P. Nogueira, H. J. Haugen, D. Josefsen, S. Krauss, A. van Apeldoorn, P. Gatenholm, H. Scholz

This study shows that adipose-derived stromal cells improve islet survival and function in a 3D bioprinted scaffold, offering a potential cell therapy for diabetes.

bioRxiv · May 30, 2022Cell Biology

SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model

B. L. Haagmans, D. Noack, N. M. A. Okba, W. LI, C. Wang, T. Bestebroer, R. de Vries, S. Herfst, D. de Meulder, P. van Run, M. M. Lamers, B. Rijnders, C. Rokx, F. J. M. van Kuppeveld, F. Grosveld, , B. Rockx

This study shows that high-dose convalescent plasma or monoclonal antibodies protect hamsters from SARS-CoV-2-induced lower respiratory disease, but lower doses are ineffective.

bioRxiv · Aug 24, 2020Microbiology

Oxidative stress in alpha and beta cells as a selection criterion for biocompatible biomaterials

M. M. Sthijns, M. J. Jetten, S. G. Mohammed, S. M. Claessen, R. de Vries, A. Stell, D. de Bont, M. A. Engelse, D. Mumcuoglu, C. A. van Blitterswijk, P. Y. Dankers, E. J. de Koning, A. A. van Apeldoorn, V. L. LaPointe

The paper evaluates five polymers for their effect on oxidative stress and islet function, identifying PEOT/PBT300 as a promising biomaterial for islet encapsulation due to its reduced oxidative stress and improved viability.

bioRxiv · Aug 8, 2019 · PreprintCell Biology

Real-time assembly of an artificial virus elucidated at the single-particle level

M. Marchetti, D. Kamsma, E. Cazares Vargas, A. Hernandez Garcia, P. van der Schoot, R. de Vries, G. J. L. Wuite, W. H. Roos

This study uses single-molecule techniques to track real-time assembly of artificial virus-like particles, revealing nucleation and DNA packaging mechanisms.

bioRxiv · Jan 22, 2019Biophysics