Tetracistronic Minigenomes Elucidate a Functional Promoter for Ghana Virus and Unveils Cedar Virus Replicase Promiscuity for all Henipaviruses
G. D. Haas, K. S. Schmitz, K. D. Azarm, K. N. Johnson, W. R. Klain, A. N. Freiberg, R. M. Cox, R. K. Plemper, B. Lee
This paper develops tetracistronic minigenomes for henipaviruses to model their life cycle outside high biocontainment, revealing Cedar virus replicase promiscuity and functional GhV replicase with antiviral efficacy.
Journal of Virology · Oct 22, 2024Peer-reviewedMicrobiology