Author

F. Klauschen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4 Cell Biology· 1

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

B. Obermayer· 3 shared D. Beule· 3 shared A. Elsner· 2 shared A. Trinks· 2 shared C. Falk· 2 shared C. Sers· 2 shared D. Horst· 2 shared J. Neudecker· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

B. Obermayer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Slow integrin-dependent migration organizes networks of tissue-resident mast cells

S. K. Bambach, L. Kaltenbach, N. Aizarani, P. Martzloff, A. Gavrilov, K. M. Glaser, R. Thünauer, M. Mihlan, M. Stecher, A. Thiriot, S. Wienert, U. H. von Andrian, M. Schmidt-Supprian, C. Nerlov, F. Klauschen, , T. Lämmermann

This study shows that mast cells use slow integrin-dependent migration to form tissue networks, differing from other leukocytes that use fast adhesion-free movement.

bioRxiv · Jul 19, 2022 · PreprintCell Biology

Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma

T. L. B. Hoelting, F. Cidre-Aranaz, D. Matzek, B. Popper, S. J. Jacobi, J. Li, I. Piseddu, B. L. Cadilha, S. Ledderose, J. Zwilling, S. Ohmura, D. Anz, A. Kuenkele, F. Klauschen, T. G. P. Gruenewald, M. M. L. Knott

This paper develops a gene expression strategy that exploits neomorphic DNA-binding of fusion transcription factors in pediatric sarcomas to deliver therapeutic payloads with tumor-specific efficacy.

bioRxiv · Jan 5, 2022Cancer Biology

The single-cell transcriptional landscape of lung carcinoid tumors

P. Bischoff, A. Trinks, J. Wiederspahn, B. Obermayer, J. P. Pett, P. Jurmeister, A. Elsner, T. Dziodzio, J.-C. Rückert, J. Neudecker, C. Falk, D. Beule, C. Sers, M. Morkel, D. Horst, , N. Blüthgen

This study uses single-cell RNA sequencing to analyze lung carcinoid tumors, revealing their cellular composition, gene expression profiles, and potential therapeutic targets.

bioRxiv · Dec 7, 2021Cancer Biology

Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma

P. Bischoff, A. Trinks, B. Obermayer, J. P. Pett, A. Lehmann, P. Jurmeister, A. Elsner, T. Dziodzio, J.-C. Rückert, J. Neudecker, C. Falk, D. Beule, C. Sers, M. Morkel, D. Horst, , F. Klauschen

The paper uses single-cell RNA sequencing to identify two distinct tumor microenvironmental patterns in lung adenocarcinoma, associated with different prognostic outcomes.

bioRxiv · Dec 11, 2020Cancer Biology

Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC

C. Messerschmidt, B. Obermayer, K. Klinghammer, S. Ochsenreither, D. Treue, A. Stenzinger, H. Glimm, S. Fröhling, T. Kindler, C. H. Brandts, K. Schulze-Osthoff, W. Weichert, I. Tinhofer, F. Klauschen, U. Keilholz, , D. T. Rieke

The paper identifies an APOBEC-enriched subgroup of HPV-negative HNSCC with distinct immunogenic features linked to immune evasion and potential response to immunotherapy.

bioRxiv · Mar 28, 2019Cancer Biology