Cell BiologybioRxivPreprint
Homeostatic feedback between lysosomal mTORC1 and mTORC2-AKT signaling controls nutrient uptake in brown adipose tissue
G. Liebscher, N. Vujic, R. Schreiber…·L. A. Huber
The paper shows that LAMTOR2 deletion in adipocytes causes insulin-independent AKT hyperphosphorylation, leading to increased glucose and fatty acid uptake and glycogen storage in brown adipose tissue.
DOI 10.1101/2022.05.17.492242