Author

C. J. Henderson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

C. R. Wolf· 3 shared F. Inesta-Vaquera· 2 shared T. G. Frangova· 2 shared A. McLaren· 1 shared A. T. Dinkova-Kostova· 1 shared J. Grigg· 1 shared L. Miyashita· 1 shared L. P. Acosta-Jimenez· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

C. R. Wolf

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Defining the in vivo mechanism of air pollutant toxicity using murine stress response biomarkers.

F. Inesta-Vaquera, L. Miyashita, C. J. Henderson, J. Grigg, R. Wolf

This study uses murine stress response biomarkers to investigate the mechanisms of air pollutant toxicity and links pollutant exposure to health risks.

bioRxiv · Oct 5, 2022Pharmacology & Toxicology

Quantifying ERK-activity in response to inhibition of the BRAFV600E-MEK-ERK cascade using mathematical modelling

S. Hamis, Y. Kapelyukh, A. McLaren, C. J. Henderson, C. R. Wolf, M. A. J. Chaplain

This study develops a mathematical model to quantify how dabrafenib and trametinib inhibit ERK-activity in BRAFV600E-mutant melanoma cells and identify mechanisms of drug resistance.

bioRxiv · Apr 20, 2021Cancer Biology

Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity.

F. Inesta-Vaquera, P. Navasumrit, C. J. Henderson, T. G. Frangova, T. Honda, A. T. Dinkova-Kostova, M. Ruchirawat, C. R. Wolf

This study uses Hmox1 reporter mice to demonstrate iAs-induced oxidative stress and validate N-acetyl cysteine as a potential therapy for arsenic toxicity.

bioRxiv · Jun 19, 2020Pharmacology & Toxicology

Measuring physiological responses to stressors using a novel Hmox1 reporter mouse

M. McMahon, S. Ding, L. P. Acosta-Jimenez, T. G. Frangova, C. J. Henderson, C. R. Wolf

This paper develops a novel Hmox1 reporter mouse to measure physiological responses to stressors, showing it accurately reflects oxidative and inflammatory stimuli.

bioRxiv · Jan 5, 2017Physiology