Author

C. J. Henry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. C. Porter· 3 shared E. C. Dreaden· 3 shared P. Do· 3 shared R. Hunter· 2 shared A. Chang· 1 shared A. Chyong· 1 shared A. J. Kinloch· 1 shared A. J. Ross· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBioengineering

C. C. Porter

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The T-cell niche tunes immune function through modulation of the cytoskeleton and TCR-antigen forces

A. V. Kellner, R. Hunter, P. Do, J. Eggert, M. Jaffe, D. K. Geitgey, M. Lee, J. A. G. Hamilton, A. J. Ross, R. S. Ank, R. L. Bender, R. Ma, C. C. Porter, E. C. Dreaden, B. B. Au-Yeung, , K. Salaita

This study shows that the adipocyte niche impairs T-cell function by modulating cytoskeletal dynamics and reducing TCR-antigen forces in both mice and human T-cells.

bioRxiv · Jan 31, 2024 · PreprintBioengineering

Multicolor Light-Induced Immune Activation via Polymer Photocaged Cytokines

L. A. Birnbaum, E. C. Sullivan, P. Do, B. Uricoli, C. C. Porter, C. J. Henry, E. C. Dreaden

This paper develops a method to control cytokine activity using light, enabling spatial and temporal regulation of immune responses ex vivo.

bioRxiv · Oct 3, 2022Bioengineering

In situ humoral selection in human lupus tubulointerstitial inflammation

A. J. Kinloch, Y. Asano, A. Mohsin, C. J. Henry, R. Abraham, A. Chang, C. Labno, P. C. Wilson, M. R. Clark

The paper shows that anti-vimentin antibodies in lupus nephritis undergo in situ selection for enhanced binding and specificity to vimentin fibrils, challenging the notion of affinity maturation as a non-specific consequence of polyreactivity.

bioRxiv · Jun 29, 2020 · PreprintImmunology

Rapid Assembly and Screening of Multivalent Immune Cell-Redirecting Therapies for Leukemia

P. Do, L. A. Perdue, A. Chyong, R. Hunter, J. Dougan, C. J. Henry, C. C. Porter, E. C. Dreaden

This paper develops a method to rapidly assemble and screen multivalent immune cell-redirecting therapies for leukemia, identifying compounds with lytic activity comparable to existing treatments.

bioRxiv · May 8, 2020Bioengineering