Author

C. Jayaprakash

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Pereira de Freitas· 1 shared B. Gielniewski· 1 shared B. Kaminska· 1 shared B. Kaza· 1 shared G. Giuliani· 1 shared J. Das· 1 shared J. Mieczkowski· 1 shared J. Trubicka· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Pereira de Freitas

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2 papers

Recent·Most cited

Spatial organization and stochastic fluctuations of immune cells impact clinical responsiveness to immune checkpoint inhibitors in patients with melanoma

G. Giuliani, W. Stewart, Z. Li, C. Jayaprakash, J. Das

The paper develops a spatially resolved model to show how immune cell organization and dynamics influence response to immune checkpoint inhibitors in melanoma patients.

bioRxiv · Dec 6, 2023 · PreprintImmunology

H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in paediatric high-grade glioma cells

K. B. Leszczynska, A. Pereira de Freitas, C. Jayaprakash, M. Dzwigonska, K. Wojnicki, B. Gielniewski, P. Szadkowska, B. Kaza, M. K. Ciolkowski, J. Trubicka, W. Grajkowska, B. Kaminska, J. Mieczkowski

This study shows HDAC inhibitors reduce H3.3K27M protein levels in glioma cells, with H2A.Z facilitating this effect, suggesting a potential therapeutic strategy for DIPG.

bioRxiv · May 15, 2023Cancer Biology