Author

B. Kaza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Gielniewski· 2 shared B. Kaminska· 2 shared F. Feldmann· 2 shared P. Szadkowska· 2 shared P. W. Hanley· 2 shared A. Koziarski· 1 shared A. Marchel· 1 shared A. Marzi· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

B. Gielniewski

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in paediatric high-grade glioma cells

K. B. Leszczynska, A. Pereira de Freitas, C. Jayaprakash, M. Dzwigonska, K. Wojnicki, B. Gielniewski, P. Szadkowska, B. Kaza, M. K. Ciolkowski, J. Trubicka, W. Grajkowska, B. Kaminska, J. Mieczkowski

This study shows HDAC inhibitors reduce H3.3K27M protein levels in glioma cells, with H2A.Z facilitating this effect, suggesting a potential therapeutic strategy for DIPG.

bioRxiv · May 15, 2023Cancer Biology

Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine

K. L. O'Donnell, F. Feldmann, B. Kaza, C. S. Clancy, P. W. Hanley, P. Fletcher, A. Marzi

A single low-dose VSV-based vaccine protects nonhuman primates from lethal Marburg virus disease regardless of administration timing.

bioRxiv · Sep 17, 2022Immunology

UK B.1.1.7 variant exhibits increased respiratory replication and shedding in nonhuman primates

K. Rosenke, F. Feldmann, A. Okumura, F. Hansen, T.-L. Tang-Huau, K. Meade-White, B. Kaza, B. J. Smith, P. W. Hanley, J. Lovaglio, M. Jarvis, C. Shaia, H. Feldmann

This study compares the respiratory replication and shedding of SARS-CoV-2 D614G and B.1.1.7 variants in African green monkeys, finding increased respiratory replication for B.1.1.7 but no disease enhancement.

bioRxiv · Jun 11, 2021Microbiology

The novel, recurrent mutation in the TOP2A gene results in the enhanced topoisomerase activity and transcription deregulation in glioblastoma

B. Gielniewski, K. Poleszak, A.-J. Roura, P. Szadkowska, S. K. Krol, R. Guzik, P. Wiechecka, M. Maleszewska, B. Kaza, A. Marchel, T. Czernicki, A. Koziarski, G. Zielinski, A. Styk, M. Kawecki, , B. Kaminska

The paper identifies a novel TOP2A mutation in glioblastomas that enhances DNA binding and transcriptional activity, correlating with poorer patient survival.

bioRxiv · Jun 17, 2020 · PreprintCancer Biology