Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms
G. Gogl, K. V. Tugaeva, P. Eberling, C. Kostmann, G. Trave, N. N. Sluchanko
The paper investigates the binding preferences of seven human 14-3-3 isoforms to phospho-motifs in E6 oncoproteins and RSK1, revealing a conserved binding hierarchy across targets.
bioRxiv · Jul 24, 2020Biochemistry