Author

C. L. Myers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:machine learning (classical)· 2 Research Focus:protein folding & dynamics· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Schmidt· 2 shared W. Coyote-Maestas· 2 shared Y. He· 2 shared A. Hebert· 1 shared A. Higbee· 1 shared A. Suma· 1 shared B. J. Steffenson· 1 shared C. D. Hirsch· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

D. Schmidt

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Author profile →

5 papers

Recent·Most cited

Machine Learning Investigation Of Gene Expression Datasets Reveals TP53 Mutant-like AML With Wild Type TP53 And Poor Prognosis

Y. Lee, L. B. Baughn, Z. Sachs, C. L. Myers

This study uses machine learning to identify a TP53 mutant-like AML subtype with poor prognosis in TP53 wild-type cases, characterized by distinct gene expression and drug sensitivity profiles.

bioRxiv · Feb 22, 2023 · PreprintCancer Biology

Identification of candidate susceptibility genes to Puccinia graminis f. sp. tritici in wheat

E. C. Henningsen, V. Omidvar, R. Della Coletta, J.-M. Michno, E. Gilbert, F. Li, M. Miller, C. L. Myers, S. P. Gordon, J. P. Vogel, B. J. Steffenson, S. F. Kianian, C. D. Hirsch, M. Figueroa

The paper identifies candidate susceptibility genes to wheat stem rust disease by analyzing gene expression changes in susceptible and resistant wheat genotypes and a non-host plant.

bioRxiv · Jan 23, 2021Plant Biology

The biophysical basis of protein domain compatibility

W. Coyote-Maestas, D. Nedrud, A. Suma, Y. He, K. A. Matreyek, D. M. Fowler, V. Carnevale, C. L. Myers, D. Schmidt

The paper uses high-throughput assays and machine learning to model biophysical interactions governing protein domain compatibility in fusion proteins.

bioRxiv · Dec 9, 2020 · PreprintBiophysics

Domain Insertion Permissibility is a Measure of Engineerable Allostery in Ion Channels

W. Coyote-Maestas, Y. He, C. L. Myers, D. Schmidt

The paper introduces domain insertion permissibility as a metric to identify engineerable allosteric sites in ion channels, showing light sensitivity when inserted into allosteric sites.

bioRxiv · Aug 9, 2018Biochemistry

Chemical genomic guided engineering of gamma-valerolactone tolerant yeast

S. Bottoms, Q. Dickinson, M. McGee, L. Hinchman, A. Higbee, A. Hebert, J. Serate, D. Xie, Y. Zhang, J. J. Coon, C. L. Myers, R. Landick, J. S. Piotrowski

The paper engineers a GVL-tolerant yeast strain by deleting PAD1 and FDC1, enhancing ergosterol content and improving fermentation in GVL-containing hydrolysates.

bioRxiv · Nov 4, 2017Bioengineering