Author

C. L. Shaffer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

P. P. Damke· 2 shared C. Bryant· 1 shared C. R. Wood· 1 shared D. Ghosal· 1 shared G. J. Jensen· 1 shared L. A. Rettberg· 1 shared M. E. Ryan· 1 shared M. J. Sheedlo· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

P. P. Damke

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Author profile →

3 papers

Recent·Most cited

Architectural asymmetry enables DNA transport through the Helicobacter pylori cag type IV secretion system

M. E. Ryan, P. P. Damke, C. Bryant, M. J. Sheedlo, C. L. Shaffer

The paper shows architectural asymmetry in the Helicobacter pylori cag T4SS enables DNA translocation while allowing protein and peptidoglycan effector transport.

bioRxiv · Jul 25, 2023 · PreprintMicrobiology

Helicobacter pylori provokes STING immunosurveillance via trans-kingdom conjugation

P. P. Damke, C. R. Wood, C. L. Shaffer

This study shows Helicobacter pylori uses its cag T4SS to deliver DNA to host cells, activating STING signaling and promoting chronic infection.

bioRxiv · Jun 29, 2022 · PreprintMicrobiology

In vivo structures of the Helicobacter pylori cag type IV secretion system

Y.-W. Chang, C. L. Shaffer, L. A. Rettberg, D. Ghosal, G. J. Jensen

This study uses electron cryotomography to reveal the in vivo structure of the Helicobacter pylori cag T4SS, showing its architecture and proposed delivery mechanism.

bioRxiv · Sep 28, 2017Microbiology