Prodomain-Growth Factor Swapping in the Structure of pro-TGF-β1
B. Zhao, S. Xu, X. Dong, C. Lu, T. A. Springer
The paper determines the structure of pro-TGF-β1 with a cleavage site mutation, revealing prodomain-GF domain swapping in the dimeric structure and its implications for TGF-β biosynthesis.
bioRxiv · Jul 18, 2017Biochemistry