Author

C. M. Isacke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

L. Jenkins· 2 shared S. Haider· 2 shared A. Abaurrea· 1 shared A. Carracedo· 1 shared A. M. Araujo· 1 shared A. Tzankov· 1 shared A. Urruticoechea· 1 shared A. van Weverwijk· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

L. Jenkins

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stromal Oncostatin M axis promotes breast cancer progression

A. M. Araujo, A. Abaurrea, P. Azcoaga, J. I. Lopez-Velazco, R. Rezola, I. Osorio-Querejeta, F. Valdes-Mora, J. M. Flores, L. Jenkins, P. Fernandez-Nogueira, N. Ferrari, N. Martin-Martin, A. Tzankov, S. Eppenberger-Castori, I. Alvarez-Lopez, , C. H. Lawrie

This study identifies the stromal OSM:OSMR axis as a key driver of breast cancer progression by reprogramming the tumor microenvironment.

bioRxiv · Oct 30, 2020Cancer Biology

Therapy-induced normal tissue damage promotes breast cancer metastasis

D. W. Perkins, I. Steiner, S. Haider, D. Roberston, R. Buus, L. O'Leary, C. M. Isacke

This study shows that chemotherapy-induced normal tissue damage promotes breast cancer metastasis through pro-tumourigenic factors and extracellular matrix remodeling.

bioRxiv · Oct 17, 2020Cancer Biology

Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis

U. Jungwirth, A. van Weverwijk, L. Jenkins, J. Alexander, D. Vicente, Q. Gao, S. Haider, M. Iravani, C. M. Isacke

The paper identifies a specific cancer-associated fibroblast subset that supports tumour growth and metastasis by expressing Endo180, and shows that targeting this subset can limit tumour progression.

bioRxiv · May 17, 2020Cancer Biology