Author

C. M. Lau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

E. K. Santosa· 2 shared J. C. Sun· 2 shared A. Khodadadi-Jamayran· 1 shared A. M. Mujal· 1 shared A. Straub· 1 shared A. Tsirigos· 1 shared B. Reizis· 1 shared C. S. Leslie· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

E. K. Santosa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Step-wise epigenetic signal integration governs adaptive programming of cytotoxic lymphocytes

S. Grassmann, E. K. Santosa, H. Kim, I. B. Johnson, A. M. Mujal, J.-B. LeLuduec, S. X. Fan, M. Owyong, A. Straub, L. Deng, C. M. Lau, K. Hsu, D. Busch, J. C. Sun

This study shows that interleukin-12 signaling integrates with antigen receptor signals in a context-dependent manner to determine the epigenetic and functional fate of cytotoxic lymphocytes.

bioRxiv · Nov 7, 2023 · PreprintImmunology

3D Chromatin Dynamics during Innate and Adaptive Immune Memory Acquisition

E. K. Santosa, C. M. Lau, M. Sahin, C. S. Leslie, J. C. Sun

This study investigates 1D and 3D chromatin dynamics during immune memory formation in innate and adaptive lymphocytes using histone profiling, ATAC-seq, RNA-seq, and HiC.

bioRxiv · Jan 16, 2023 · PreprintImmunology

Genome-wide analysis of dendritic cell differentiation

I. Tiniakou, P.-F. Hsu, L. S. Lopez-Zepeda, C. M. Lau, C. Soni, E. Esteva, N. Adams, F. Liu, A. Khodadadi-Jamayran, T. Rodrick, D. Jones, A. Tsirigos, U. Ohler, M. T. Bedford, S. D. Nimer, B. Reizis

This study uses a genome-wide CRISPR/Cas9 screen to identify regulators of dendritic cell differentiation in a Flt3L-dependent murine progenitor cell line.

bioRxiv · May 11, 2022 · PreprintImmunology