Author

A. Khodadadi-Jamayran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

A. Tsirigos· 3 shared B. G. Neel· 2 shared J. Jen· 2 shared K. H. Tang· 2 shared K.-K. Wong· 2 shared T. Rodrick· 2 shared A. Athanas· 1 shared A. D. Corrado· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCancer Biology

A. Tsirigos

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability

N. Ravn-Boess, N. Roy, T. Hattori, D. Bready, H. Donaldson, C. Lawson, C. Lapierre, A. Korman, T. Rodrick, E. Liu, J. D. Frenster, G. Stephan, J. Wilcox, A. D. Corrado, J. Cai, , D. G. Placantonakis

This study identifies CD97 as a targetable vulnerability in glioblastoma through its role in tumor metabolism and signaling, supported by transcriptomic, proteomic, and functional analyses.

Cell Reports · Nov 1, 2023Peer-reviewedCancer Biology

Genome-wide analysis of dendritic cell differentiation

I. Tiniakou, P.-F. Hsu, L. S. Lopez-Zepeda, C. M. Lau, C. Soni, E. Esteva, N. Adams, F. Liu, A. Khodadadi-Jamayran, T. Rodrick, D. Jones, A. Tsirigos, U. Ohler, M. T. Bedford, S. D. Nimer, B. Reizis

This study uses a genome-wide CRISPR/Cas9 screen to identify regulators of dendritic cell differentiation in a Flt3L-dependent murine progenitor cell line.

bioRxiv · May 11, 2022 · PreprintImmunology

Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC

K. H. Tang, S. Li, A. Khodadadi-Jamayran, J. Jen, H. Han, K. Guidry, T. Chen, Y. Hao, C. Fedele, J. Zebala, D. Maeda, J. Christensen, P. Olson, A. Athanas, K.-K. Wong, B. G. Neel

This study shows that combining SHP2 and CXCR1/2 inhibitors enhances anti-tumor T cell responses in NSCLC by reducing immunosuppressive gMDSCs and promoting effector T cells.

bioRxiv · Mar 21, 2021Cancer Biology

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer

C. A. Chang, J. Jen, S. Jiang, A. Sayad, A. S. Mer, K. R. Brown, A. Nixon, A. Dhabaria, K. H. Tang, D. Venet, C. Sotiriou, J. Deng, K.-k. Wong, S. Adams, P. Meyn, , B. G. Neel

This study identifies drug-tolerant persisters (DTPs) in HER2+ breast cancer and reveals their origins and vulnerabilities to TKI resistance.

bioRxiv · Aug 28, 2020Cancer Biology

Defining Epidermal Stem Cell Fate Infidelity and Immunogenicity in Hidradenitis Suppurativa at the Single-Cell Resolution

M. Marohn, M.-j. Lin, W.-w. Yu, C. M. Mendoza, J. Remark, A. Khodadadi-Jamayran, E. S. Chiu, C. P.-J. Lu

This study identifies stem cell fate infidelity and immune interactions in HS sinus tracts using single-cell transcriptomics.

bioRxiv · Apr 21, 2020 · PreprintCell Biology