Author

U. Ohler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 5 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Research Focus:differential expression· 5 Approach:experimental assay· 5 Research Focus:gene regulatory network inference· 5 Organism:Arabidopsis· 4 Assay:scRNA-seq· 4 Assay:bulk RNA-seq· 2 Assay:multiome· 2

Frequent Co-Authors

C.-W. Hsu· 3 shared I. W. Taylor· 3 shared P. N. Benfey· 3 shared C. Schmitz-Linneweber· 2 shared R. Shahan· 2 shared T. M. Nolan· 2 shared A. Afanassiev· 1 shared A. Auger· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersPlant Biology

C.-W. Hsu

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Author profile →

7 papers

Recent·Most cited

MatK impacts Differential Chloroplast Translation of Ribosomal and Photosynthetic genes by limiting spliced tRNA-K(UUU) abundance

J. M. Muino, Y. Qu, H. Ruwe, S. Maschmann, W. Chen, R. Zoschke, U. Ohler, K. Kaufmann, C. Schmitz-Linneweber

The paper investigates how MatK affects chloroplast translation by influencing tRNA-K(UUU) abundance, leading to differential expression of ribosomal and photosynthetic genes.

bioRxiv · Oct 25, 2023 · PreprintPlant Biology

Brassinosteroid gene regulatory networks at cellular resolution

T. M. Nolan, N. Vukasinovic, C.-W. Hsu, J. Zhang, I. Vanhoutte, R. Shahan, I. W. Taylor, L. Greenstreet, M. Heitz, A. Afanassiev, P. Wang, P. Szekely, A. Brosnan, Y. Yin, G. Schiebinger, , P. N. Benfey

The paper identifies BR-responsive gene expression in Arabidopsis root cells using single-cell RNA-sequencing and reveals HAT7 and GTL1 as transcription factors regulating cell elongation.

bioRxiv · Sep 16, 2022 · PreprintPlant Biology

Arabidopsis uses a molecular grounding mechanism and a biophysical circuit breaker to limit floral abscission signaling

I. W. Taylor, O. R. Patharkar, C.-W. Hsu, J. Baer, M. Mijar, C. E. Niederhuth, U. Ohler, P. N. Benfey, J. C. Walker

This study identifies MKP1 as a negative regulator of the HAE/HSL2 abscission pathway in Arabidopsis and shows how IDA expression patterns act as a biophysical circuit breaker to terminate signaling.

bioRxiv · Jul 14, 2022Plant Biology

Genome-wide analysis of dendritic cell differentiation

I. Tiniakou, P.-F. Hsu, L. S. Lopez-Zepeda, C. M. Lau, C. Soni, E. Esteva, N. Adams, F. Liu, A. Khodadadi-Jamayran, T. Rodrick, D. Jones, A. Tsirigos, U. Ohler, M. T. Bedford, S. D. Nimer, B. Reizis

This study uses a genome-wide CRISPR/Cas9 screen to identify regulators of dendritic cell differentiation in a Flt3L-dependent murine progenitor cell line.

bioRxiv · May 11, 2022 · PreprintImmunology

A single cell Arabidopsis root atlas reveals developmental trajectories in wild type and cell identity mutants

R. Shahan, C.-W. Hsu, T. M. Nolan, B. J. Cole, I. W. Taylor, A. H. C. Vlot, P. N. Benfey, U. Ohler

The paper constructs a single-cell atlas of Arabidopsis root development and identifies an alternative pathway for endodermal identity specification in mutants.

bioRxiv · Jun 29, 2020 · PreprintPlant Biology

Chloroplast cold-resistance is mediated by the acidic domain of the RNA binding protein CP31A

A. Okuzaki, M.-K. Lehniger, J. Muino, B. Lenzen, T. Ruehle, D. Leister, U. Ohler, C. Schmitz-Linneweber

Cold exposure increases RNA binding of CP31A, which mediates cold resistance in Arabidopsis through its acidic domain.

bioRxiv · Dec 5, 2019Plant Biology

Integrated Proteogenomic Deep Sequencing and Analytics Accurately Identify Non-Canonical Peptides in Tumor Immunopeptidomes

C. Chong, M. Muller, H. Pak, D. Harnett, F. Huber, D. Grun, M. Leleu, A. Auger, M. Arnaud, B. J. Stevenson, J. Michaux, I. Bilic, A. Hirsekorn, L. Calviello, L. Simo-Riudalbas, , M. Bassani-Sternberg

The paper develops an MS-based proteogenomic approach to identify non-canonical HLA peptides in tumors, finding hundreds of shared and tumor-specific peptides, including an immunogenic one from ABCB5.

bioRxiv · Sep 6, 2019Cancer Biology