Author

C. M. Simon

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Kim· 1 shared C. E. Bowman· 1 shared C. Jang· 1 shared M. Noji· 1 shared N. J. Coffey· 1 shared S. Bowers· 1 shared W. Zhao· 1 shared Y. Jiang· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

B. Kim

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1 paper

Recent·Most cited

HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell Renal Cell Carcinoma

W. Zhao, B. Kim, N. J. Coffey, S. Bowers, Y. Jiang, C. E. Bowman, M. Noji, C. Jang, C. M. Simon, Z. Arany, B. Kim

This study shows HIF2α prevents GLS1 clustering in mitochondria, protecting ccRCC cells from glutamine deprivation, and suggests targeting GLS1 clustering could enhance HIF2 therapy.

bioRxiv · May 4, 2024Cancer Biology