Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance
C. M. Yamazaki, A. Yamaguchi, Y. Anami, W. Xiong, Y. Otani, J. Lee, N. T. Ueno, N. Zhang, Z. An, K. Tsuchikama
This study develops dual-payload antibody-drug conjugates to overcome breast tumor heterogeneity and drug resistance, showing improved efficacy in a xenograft model.
Nature Communications · Jun 10, 2021Peer-reviewedBioengineering