Structural transitions in the GTP cap visualized by cryo-EM of catalytically inactive microtubules
B. J. LaFrance, J. Roostalu, G. Henkin, B. J. Greber, R. Zhang, D. Normanno, C. McCollum, T. Surrey, E. Nogales
The paper uses cryo-EM to visualize the structure of GTP-bound microtubules, revealing an expanded lattice and closed seam that stabilize the GTP cap.
bioRxiv · Aug 13, 2021Biophysics