Author

C. Otter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

L. H. Tan· 2 shared S. R. Weiss· 2 shared A. Fausto· 1 shared A. Fehr· 1 shared C. Comar· 1 shared D. Renner· 1 shared E. Doerger· 1 shared J. Pfannenstiel· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

L. H. Tan

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Infection of primary nasal epithelial cells differentiates among lethal and seasonal human coronaviruses

C. Otter, A. Fausto, L. H. Tan, N. A. Cohen, S. R. Weiss

This study compares the infection effects of lethal and seasonal human coronaviruses in nasal epithelial cells, finding differences in cytotoxicity and barrier disruption.

bioRxiv · Oct 17, 2022Microbiology

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

C. Comar, C. Otter, J. Pfannenstiel, E. Doerger, D. Renner, L. H. Tan, S. Perlman, N. Cohen, A. Fehr, S. R. Weiss

This study shows that MERS-CoV's EndoU and accessory proteins NS4a/NS4b together suppress innate immunity, enabling viral replication, unlike SARS-CoV-2 which activates these pathways.

bioRxiv · Dec 20, 2021 · PreprintMicrobiology