Author

N. A. Cohen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:bulk RNA-seq· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. R. Weiss· 4 shared L. H. Tan· 3 shared A. Fausto· 2 shared C. J. Otter· 2 shared A. Asthana· 1 shared A. D. Marques· 1 shared A. E. Vaughan· 1 shared A. Jaquish· 1 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersMicrobiology

S. R. Weiss

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

C. J. Otter, N. Bracci, N. A. Parenti, C. Ye, T. Li Hui, A. Asthana, J. J. Pfannenstiel, N. Jackson, A. R. Fehr, R. H. Silverman, N. A. Cohen, L. Martinez-Sobrido, S. R. Weiss

This study shows that SARS-CoV-2 nsp15 inhibits dsRNA-induced antiviral signaling, which is necessary for viral replication in nasal epithelial cultures.

Proceedings of the National Academy of Sciences · Apr 3, 2024Peer-reviewedMicrobiology

Interferon signaling in the nasal epithelium distinguishes among lethal and common cold respiratory viruses and is critical for viral clearance

C. J. Otter, D. M. Renner, A. Fausto, L. H. Tan, N. A. Cohen, S. R. Weiss

The paper examines how interferon signaling in nasal epithelial cells differentiates between common cold and lethal respiratory viruses, showing its role in viral clearance.

bioRxiv · Dec 18, 2023 · PreprintMicrobiology

Comparison of SARS-CoV-2 variants of concern in primary human nasal cultures demonstrates Delta as most cytopathic and Omicron as fastest replicating

N. S. Tanneti, A. K. Patel, L. H. Tan, A. D. Marques, R. A. Perera, S. Sherrill-Mix, B. J. Kelly, R. G. Collman, K. Rodino, C. Lee, F. D. Bushman, N. A. Cohen, S. R. Weiss

The paper compares SARS-CoV-2 variants of concern in nasal and lung cultures, finding Omicron replicates fastest and Delta causes most cellular damage.

bioRxiv · Aug 24, 2023Microbiology

Taste receptor T1R3 in nasal cilia detects Staphylococcus aureus D-amino acids to increase apical glucose uptake and enhance innate immunity

R. M. Carey, B. M. Hariri, N. D. Adappa, J. N. Palmer, R. F. Margolskee, N. A. Cohen, R. J. Lee

The paper shows that T1R3 in nasal cilia detects D-amino acids from Staphylococcus aureus to reduce airway surface liquid glucose and enhance innate immunity.

bioRxiv · Oct 21, 2022 · PreprintPhysiology

Infection of primary nasal epithelial cells differentiates among lethal and seasonal human coronaviruses

C. Otter, A. Fausto, L. H. Tan, N. A. Cohen, S. R. Weiss

This study compares the infection effects of lethal and seasonal human coronaviruses in nasal epithelial cells, finding differences in cytotoxicity and barrier disruption.

bioRxiv · Oct 17, 2022Microbiology

Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair

J. Barr, M. E. Gentile, S. Lee, M. Kotas, M. Fernanda de Mello Costa, N. P. Holcomb, A. Jaquish, G. Palashikar, I. Matsumoto, R. Margolskee, N. A. Cohen, X. Sun, A. E. Vaughan

The paper identifies heterogeneous tuft cells in injured lungs that develop independently of Type 2 cytokines and are not essential for dysplastic repair.

bioRxiv · Mar 10, 2022Cell Biology