Author

C. P. Herlihy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

E. A. Crowley· 2 shared A. L. Manning· 1 shared A. Manning· 1 shared A. Pombo· 1 shared A. Willemin· 1 shared C.-t. Wu· 1 shared G. M. Church· 1 shared J. Stein· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

E. A. Crowley

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Author profile →

3 papers

Recent·Most cited

Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues

J. Stein, M. Ericsson, M. Nofal, L. Magni, S. Aufmkolk, R. B. McMillan, L. Breimann, C. P. Herlihy, S. D. Lee, A. Willemin, J. Wohlmann, L. Arguedas-Jimenez, P. Yin, A. Pombo, G. M. Church, C.-t. Wu

The paper introduces tkPAINT, a method combining TIRF microscopy and Tokuyasu cryosectioning to enhance DNA-PAINT for single-protein imaging and molecular counting with 3 nm precision across cells and tissues.

bioRxiv · Feb 5, 2024Cell Biology

Suv420 enrichment at the centromere limits Aurora B localization and function

C. P. Herlihy, S. Hahn, E. A. Crowley, N. Hermance, A. Manning

This study shows that Suv420 enrichment at centromeres reduces Aurora B localization, leading to mitotic errors and chromosome missegregation, with implications for cancer.

bioRxiv · Jun 14, 2021Cell Biology

Suppression of chromosome instability limits acquired drug resistance

E. A. Crowley, N. M. Hermance, C. P. Herlihy, A. L. Manning

This study shows that suppressing chromosome instability reduces acquired drug resistance in non-small cell lung cancer by altering molecular mechanisms, without affecting tumor growth.

bioRxiv · Jul 10, 2020Cancer Biology