Author

C. Parola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

S. T. Reddy· 3 shared D. M. Mason· 2 shared L. Csepregi· 2 shared A. R. G. de Vries· 1 shared C. R. Weber· 1 shared D. Kitamura· 1 shared D. Neumeier· 1 shared L. Bonati· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

S. T. Reddy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Convergent selection in antibody repertoires is revealed by deep learning

S. Friedensohn, D. Neumeier, T. A. Khan, L. Csepregi, C. Parola, A. R. G. de Vries, L. Erlach, D. M. Mason, S. T. Reddy

This study uses deep learning to identify convergent antibody sequences in mice, showing their antigen-specificity and potential for immunodiagnostics.

bioRxiv · Feb 25, 2020 · PreprintImmunology

Molecular design, optimization and genomic integration of chimeric B cell receptors in murine B cells

T. Pesch, L. Bonati, W. Kelton, C. Parola, R. A. Ehling, L. Csepregi, D. Kitamura, S. T. Reddy

The paper designs, optimizes, and genomically integrates chimeric B cell receptors (CBCRs) in murine B cells using CRISPR-Cas9, demonstrating robust surface expression and antigen recognition.

bioRxiv · Jun 5, 2019Immunology

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis

D. M. Mason, C. R. Weber, C. Parola, S. M. Meng, V. Greiff, W. J. Kelton, S. T. Reddy

This paper develops a high-throughput method for antibody engineering in mammalian cells using CRISPR/Cas9-mediated homology-directed mutagenesis, demonstrating improved efficiency and applicability for variant discovery and optimization.

bioRxiv · Mar 19, 2018Bioengineering