Author

C. Pospori

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

R. Khorshed· 2 shared B. Partridge· 1 shared C. Christodoulidou· 1 shared C. F. Lee· 1 shared C. Georgiou· 1 shared C. L. Lo Celso· 1 shared C. Lo Celso· 1 shared D. Bonnet· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

R. Khorshed

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2 papers

Recent·Most cited

Heterogeneous run-and-tumble motion accounts for transient non-Gaussian super-diffusion in haematopoietic multi-potent progenitor cells

B. Partridge, S. Gonzalez Anton, R. Khorshed, G. Adams, C. Pospori, C. Lo Celso, C. F. Lee

The paper analyzes MPP cell trajectories from in-vivo imaging, identifies transient non-Gaussian super-diffusion, and explains it using a run-and-tumble model.

bioRxiv · Nov 19, 2021Biophysics

Dynamic regulation of hierarchical heterogeneity in Acute Myeloid Leukemia serves as a tumor immunoevasion mechanism

C. Pospori, W. Grey, S. Gonzalez-Anton, S. V. Gibson, C. Georgiou, F. Birch, G. Stevens, T. Williams, R. Khorshed, M. L. R. Haltalli, M.-N. Skoufou-Papoutsaki, K. Sloan, H. H. Encabo, J. Hopkins, C. Christodoulidou, , C. L. Lo Celso

The paper shows that hierarchical heterogeneity in AML cells, regulated by immune responses, contributes to disease progression through PDL1 upregulation and dynamic balance between proliferation and immunosuppression.

bioRxiv · Dec 21, 2020 · PreprintCancer Biology