Secreted folate receptor-gamma drives fibrogenesis in nonalcoholic steatohepatitis by amplifying TGFβ signaling in hepatic stellate cells
S. Merali, C. Quinn, C. Merali, M. C. Rico, J. Karanicolas, O. Perez-Leal, V. Mischley, S. L. Friedman
This study identifies secreted folate receptor-gamma (FOLR3) as a driver of fibrogenesis in NASH by enhancing TGFβ signaling in hepatic stellate cells.
bioRxiv · Jul 21, 2022 · PreprintBiochemistry