Emergence of Zika virus: Direct reversion of mutations and fitness restoration prior to spread to the Americas
J. Liu, Y. Liu, C. Shan, B. T. D. Nunes, R. Yun, S. L. Haller, G. H. Rafael, S. R. Azar, C. R. Andersen, K. S. Plante, N. Vasilakis, P.-Y. Shi, S. C. Weaver
This study identifies four mutations in Zika virus that reversed prior mutations, restoring fitness for urban transmission and increasing epidemic risk before the virus spread to the Americas.
bioRxiv · Jun 29, 2020 · PreprintMicrobiology