Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
20 papers
Recent·Most cited
D. P. Shinde, J. A. Plante, D. Scharton, B. Mitchel, J. Walker, S. R. Azar, R. Kroon-Campos, L. A. Sacchetto, B. P. Drumond, N. Vasilakis, K. S. Plante, S. C. Weaver
The paper shows that prior immunity to dengue and Zika viruses reduces yellow fever viremia, limiting mosquito infection and urban transmission risk.
bioRxiv · Mar 3, 2024 · PreprintMicrobiology
A. Accoti, M. Becker, A. E. I. Abu, J. Vulcan, R. Yun, S. G. Widen, M. Sylla, V. L. Popov, S. C. Weaver, L. B. Dickson
This study identifies AePer50, a gene upregulated during dehydration in Aedes aegypti, as critical for midgut infection of arboviruses under low humidity conditions.
bioRxiv · Oct 11, 2023 · PreprintMicrobiology
Z. Yang, B. A. Johnson, V. A. Meliopoulos, X. Ju, P. Zhang, M. P. Hughes, J. Wu, K. P. Koreski, T.-C. Chang, G. Wu, J. Hixon, J. Duffner, K. Wong, R. Lemieux, K. G. Lokugamage, , J. P. Taylor
This study identifies the role of G3BP1-N interaction in SARS-CoV-2 replication by showing that disrupting this interaction reduces viral replication and pathogenesis.
bioRxiv · Jun 29, 2023 · PreprintCell Biology
Y. Liu, X. Zhang, J. Liu, H. Xia, J. Zou, A. E. Muruato, S. Periasamy, J. A. Plante, N. E. Bopp, C. Kurhade, A. Bukreyev, P. Ren, T. Wang, V. D. Menachery, K. S. Plante, , P.-Y. Shi
This paper describes a live-attenuated SARS-CoV-2 vaccine candidate with deleted ORFs that shows reduced replication and attenuation in animal models, and reports its protective efficacy against wild-type virus challenge.
bioRxiv · Feb 14, 2022Microbiology
j. Zou, H. Xia, X. Xie, C. Kurhade, R. R. Machado, S. C. Weaver, P. Ren, P.-Y. Shi
This study assesses cross-neutralization against Omicron SARS-CoV-2 from prior non-Omicron infections and finds significantly lower neutralization titers compared to the original strain.
bioRxiv · Dec 20, 2021Microbiology
R. L. Hajnik, J. A. Plante, Y. Liang, M.-G. Alameh, J. Tang, C. Zhong, A. Adam, D. Scharton, G. H. Rafael, Y. Liu, N. C. Hazell, J. Sun, L. Soong, P.-Y. Shi, T. Wang, , H. Hu
This study shows that combining mRNA vaccines targeting the SARS-CoV-2 spike and nucleoprotein proteins enhances protection against the delta variant in animal models.
bioRxiv · Dec 8, 2021 · PreprintMicrobiology
A. Melton, L. A. Doyle-Meyers, R. V. Blair, C. Midkiff, H. J. Melton, K. Russell-Lodrigue, P. P. Aye, F. Schiro, M. Fahlberg, D. Szeltner, S. Spencer, B. J. Beddingfield, K. Goff, N. Golden, T. Penney, , N. J. Maness
This study shows that pigtail macaques infected with SARS-CoV-2 exhibit mild-to-moderate disease with specific immune and viral dynamics, making them a potential model for studying COVID-19.
bioRxiv · Aug 28, 2021Immunology
B. J. Beddingfield, C. Sugimoto, M. J. Kuroda, E. Wang, S. C. Weaver, K. E. Russell-Lodrigue, S. Z. Killeen, C. J. ROY
This study examines kinetic and phenotypic changes in myeloid lineage cells during early Chikungunya infection in cynomolgus macaques, revealing altered cell turnover and activation states.
bioRxiv · May 18, 2021Immunology
A. Muruato, M. Vu, B. A. Johnson, M. Davis-Gardner, A. R. Vanderheiden, K. Lokugamage, C. Schindewolf, P. A. Crocquet-Valdes, R. M. Langsjoen, J. A. Plante, K. S. Plante, S. C. Weaver, K. Debbink, A. L. Routh, D. H. Walker, , V. D. Menachery
This study creates a mouse-adapted SARS-CoV-2 strain that protects mice from lethal SARS-CoV challenge, demonstrating cross-strain immunity.
bioRxiv · May 3, 2021Microbiology
Y. Liu, J. Liu, K. S. Plante, J. A. Plante, X. Xie, X. Zhang, Z. Ku, Z. An, D. Scharton, C. Schindewolf, V. D. Menachery, P.-Y. Shi, S. C. Weaver
The paper shows the N501Y spike mutation in SARS-CoV-2 enhances viral transmission in hamsters and human airway cells by increasing receptor binding affinity.
bioRxiv · Mar 8, 2021 · PreprintMicrobiology
X. Zhang, Y. Liu, J. Liu, A. L. Bailey, K. S. Plante, J. A. Plante, J. Zou, H. Xia, N. E. Bopp, P. V. Aguilar, P. Ren, V. D. Menachery, M. S. Diamond, S. C. Weaver, X. Xie, P.-Y. Shi
This paper develops a trans-complementation system to produce single-round infectious SARS-CoV-2 at BSL-2 labs, enabling safe high-throughput testing without full viral replication.
bioRxiv · Jan 16, 2021 · PreprintMicrobiology
D. Chmielewski, J. Kaelber, J. Jin, S. C. Weaver, A. J. Auguste, W. Chiu
The paper presents a near-atomic resolution cryo-EM structure of Mayaro virus, revealing structural determinants of alphavirus particle formation and identifying key residues involved in assembly.
bioRxiv · Jan 14, 2021 · PreprintMicrobiology
J. A. Plante, Y. Liu, J. Liu, H. Xia, B. A. Johnson, K. G. Lokugamage, X. Zhang, A. E. Muruato, J. Zou, C. R. Fontes-Garfias, D. Mirchandani, D. Scharton, J. P. Bilello, Z. Ku, Z. An, , P.-Y. Shi
This study shows the D614G mutation in SARS-CoV-2 increases viral replication and upper respiratory tract viral loads but does not reduce vaccine efficacy or antibody neutralization.
bioRxiv · Sep 1, 2020Microbiology
K. S. Plante, J. A. Plante, D. Fernandez, D. Mirchandani, N. E. Bopp, P. V. Aguilar, K. J. Sastry, R. A. Newman, S. C. Weaver
This paper tests oleandrin's antiviral activity against SARS-CoV-2 in vitro, showing potent prophylactic and therapeutic effects with high dose reductions in viral production.
bioRxiv · Jul 15, 2020 · PreprintMicrobiology
J. Liu, Y. Liu, C. Shan, B. T. D. Nunes, R. Yun, S. L. Haller, G. H. Rafael, S. R. Azar, C. R. Andersen, K. S. Plante, N. Vasilakis, P.-Y. Shi, S. C. Weaver
This study identifies four mutations in Zika virus that reversed prior mutations, restoring fitness for urban transmission and increasing epidemic risk before the virus spread to the Americas.
bioRxiv · Jun 29, 2020 · PreprintMicrobiology
R. V. Blair, M. Vaccari, L. A. Doyle-Meyers, C. J. Roy, K. Russell-Lodrigue, M. Fahlberg, C. J. Monjure, B. Beddingfield, K. S. Plante, J. A. Plante, S. C. Weaver, X. Qin, C. C. Midkiff, G. Lehmicke, N. Golden, , J. Rappaport
This study compares SARS-CoV-2 infection in aged African green monkeys and rhesus macaques, finding ARDS and cytokine storms in AGMs but not RMs.
bioRxiv · Jun 18, 2020 · PreprintPathology
R. Vandergaast, T. Carey, S. Reiter, P. Lech, C. Gnanadurai, M. Tesfay, J. Buehler, L. Suksanpaisan, S. Naik, B. Brunton, J. Recker, M. Haselton, C. Ziegler, A. Roesler, J. R. Mills, , S. J. Russell
The paper develops and validates IMMUNO-COV, a high-throughput assay that accurately quantifies SARS-CoV-2-neutralizing antibodies in human sera.
bioRxiv · May 26, 2020 · PreprintImmunology
E. V. Kozlova, S. Hegde, C. M. Roundy, G. Golovko, M. A. Saldana, C. E. Hart, E. R. Anderson, E. A. Hornett, K. Khanipov, V. L. Popov, M. Pimenova, Y. Zhou, Y. Fovanov, S. C. Weaver, A. L. Routh, , G. L. Hughes
This study investigates how microbial interactions in the mosquito gut affect Serratia colonization and blood feeding behavior in Ae. aegypti.
bioRxiv · Apr 14, 2020Microbiology
J. P. Carrera, Z. M. Cucunuba, K. Neira, B. Lambert, Y. Pitti, C. Jackman, J. Liscano, J. Garzon, D. Beltran, L. Collado-Mariscal, L. Saenz, N. Sosa, L. D. Rodriguez-Guzman, P. Gonzalez, A. G. Lescano, , C. A. Donnelly
The paper investigates endemic and epidemic alphavirus infections in eastern Panama using serosurveys and statistical modeling, finding recent increases in MADV and VEEV infections.
bioRxiv · Jan 10, 2020Microbiology
B. M. Althouse, M. Guerbois, D. A. T. Cummings, O. Diop, O. Faye, A. Faye, D. Diallo, B. D. Sadio, A. Sow, O. Faye, A. A. Sall, M. Diallo, B. Benefit, E. Simmons, D. M. Watts, , K. A. Hanley
The paper investigates the role of monkeys in the sylvatic cycle of chikungunya virus in Senegal using serosurveillance and mathematical modeling, finding that monkeys act as amplification hosts rather than reservoir hosts.
bioRxiv · Oct 13, 2017Ecology