Macrophages undergo necroptosis during severe influenza A infection and contribute to virus-associated cytokine storm
A. C. Ferreira, C. Q. Sacramento, F. S. Pereira-Dutra…·T. M. L. Souza
This study shows that IAV or HA induces necroptosis in macrophages, contributing to cytokine storm and lung injury, and that anti-TNF treatment prevents these effects.