Author

A. C. Ferreira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 3 Animal Behavior & Cognition· 1 Ecology· 1 Pharmacology & Toxicology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Research Focus:host-pathogen & immune response· 6 Organism:human· 6 Research Focus:drug response / drug discovery· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

T. M. L. Souza· 7 shared C. Q. Sacramento· 6 shared J. R. Temerozo· 6 shared M. Mattos· 6 shared N. Fintelman-Rodrigues· 6 shared P. T. Bozza· 6 shared C. S. de Freitas· 4 shared D. C. Bou-Habib· 4 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

7 shared papersImmunology

T. M. L. Souza

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Macrophages undergo necroptosis during severe influenza A infection and contribute to virus-associated cytokine storm

A. C. Ferreira, C. Q. Sacramento, F. S. Pereira-Dutra, N. Fintelman-Rodrigues, P. P. Silva, M. Mattos, C. S. de Freitas, A. Marttorelli, G. R. de Melo, M. C. Macedo, I. G. Azevedo-Quintanilha, A. S. Carlos, J. V. Emidio, C. C. Garcia, P. T. Bozza, , T. M. L. Souza

This study shows that IAV or HA induces necroptosis in macrophages, contributing to cytokine storm and lung injury, and that anti-TNF treatment prevents these effects.

bioRxiv · Apr 20, 2022 · PreprintImmunology

Atazanavir is a competitive inhibitor of SARS-CoV-2 Mpro, impairing variants replication in vitro and in vivo

O. A. Chaves, C. Q. Sacramento, A. C. Ferreira, M. Mattos, N. Fintelman-Rodrigues, J. R. Temerozo, D. P. Pinto, G. P. E. da Silveira, L. B. da Fonseca, H. M. Pereira, A. S. Carlos, J. d. C. P. d'Avila, J. P. B. Viola, R. Q. Monteiro, L. Vazquez, , T. M. L. Souza

This study shows that atazanavir inhibits SARS-CoV-2 Mpro, effectively reducing replication of both B.1 and gamma variants in vitro and in vivo.

bioRxiv · Nov 24, 2021Pharmacology & Toxicology

Unlike Chloroquine, mefloquine inhibits SARS-CoV-2 infection in physiologically relevant cells and does not induce viral variants.

C. Q. Sacramento, N. Fintelman-Rodrigues, S. S. G. Dias, J. R. Temerozo, A. d. P. D. Da Silva, C. S. da Silva, A. C. Ferreira, M. Mattos, V. C. Soares, F. Pereira-Dutra, M. D. Miranda, D. F. Barreto-Vieira, M. A. N. da Silva, S. de Siqueira Santos, M. Torres, , T. M. L. Souza

This paper shows mefloquine inhibits SARS-CoV-2 infection in relevant cells more effectively than chloroquine without promoting viral mutations.

bioRxiv · Jul 21, 2021Microbiology

A \"Dirty\" Footprint: Anthropogenic Soils Promote Biodiversity in Amazonian Rainforests

W. C. Demetrio, A. C. Conrado, A. Acioli, A. C. Ferreira, M. L. Bartz, S. W. James, E. da Silva, L. S. Maia, G. C. Martins, R. S. Macedo, D. W. G. Stanton, P. Lavelle, E. Velasquez, A. Zangerle, S. Tapia-Coral, , de

The paper examines soil macroinvertebrate communities in Amazonian Dark Earths (ADEs) and finds higher biodiversity and biological activity compared to adjacent soils, highlighting the impact of human activities on Amazonian ecosystems.

Global Change Biology · Jul 10, 2021Peer-reviewedZoology

A suitable murine model for studying respiratory coronavirus infection and therapeutic countermeasures in BSL-2 laboratories

A. C. d. S. P. Andrade, G. H. Campolina-Silva, C. M. Queiroz-Junior, L. C. de Oliveira, L. d. S. B. Lacerda, J. C. Pimenta, F. R. O. de Souza, I. d. M. Chaves, I. B. Passos, D. C. Teixeira, P. G. Bittencourt-Silva, P. A. C. Valadao, L. Rossi-Oliveira, M. M. Antunes, A. F. A. Figueiredo, , Costa

This study evaluates a murine model using MHV-3 to mimic COVID-19 pathogenesis and tests TNF inhibition as a therapeutic strategy.

bioRxiv · May 28, 2021 · PreprintMicrobiology

Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

S. S. Gomes Dias, V. S. Cardoso, A. C. Ferreira, C. Q. Sacramento, N. Fintelman-Rodrigues, J. R. Temerozo, L. Teixeira, E. A. Barreto, M. Mattos, C. S. de Freitas, I. Azevedo-Quintanilha, P. P. A. Manso, E. D. Hottz, C. R. R. Pao, D. C. Bou-Habib, , P. T. Bozza

This study shows that lipid droplets support SARS-CoV-2 replication and inflammatory mediator production, with DGAT-1 inhibition reducing viral replication and inflammation.

bioRxiv · Aug 22, 2020 · PreprintImmunology

VIP plasma levels associate with survival in severe COVID-19 patients, correlating with protective effects in SARS-CoV-2-infected cells.

J. R. Temerozo, C. Q. Sacramento, N. Fintelman-Rodrigues, C. R. R. Pao, C. S. de Freitas, S. d. S. G. Dias, A. C. Ferreira, M. Mattos, V. C. Soares, L. Teixeira, I. G. de Azevedo-Quintanilha, E. D. Hottz, P. Kurtz, F. A. Bozza, P. T. Bozza, , D. C. Bou-Habib

The paper shows elevated VIP plasma levels in severe COVID-19 patients correlate with survival and protective effects against SARS-CoV-2 in vitro.

bioRxiv · Jul 25, 2020Immunology

The in vitro antiviral activity of the anti-hepatitis C virus (HCV) drugs daclatasvir and sofosbuvir against SARS-CoV-2

C. Q. Sacramento, N. Fintelman-Rodrigues, J. R. Temerozo, A. d. P. D. Da Silva, S. da Silva Gomes Dias, A. C. Ferreira, C. d. S. da Silva, M. Mattos, C. R. R. Pao, C. S. de Freitas, V. Cardoso Soares, L. V. B. Hoelz, T. V. A. Fernandes, F. S. C. Branco, M. M. Bastos, , T. M. L. Souza

This study evaluates the antiviral activity of daclatasvir and sofosbuvir against SARS-CoV-2 in vitro, showing inhibition of viral replication and associated pathologies.

bioRxiv · Jun 15, 2020 · PreprintMicrobiology

Deep learning-based methods for individual recognition in small birds

A. C. Ferreira, L. R. Silva, F. Renna, H. B. Brandl, J. P. Renoult, D. R. Farine, R. Covas, C. Doutrelant

This paper develops deep learning methods for individual bird recognition in both captive and wild settings, demonstrating their effectiveness with three bird species.

bioRxiv · Dec 3, 2019Ecology

How to make methodological decisions when inferring social networks

A. C. Ferreira, R. Covas, L. R. Silva, S. C. Esteves, I. Duarte, R. Fortuna, F. Theron, C. Doutrelant, D. R. Farine

The paper provides a framework for making methodological decisions in social network inference, emphasizing the use of a priori knowledge and pilot studies to improve network validity.

bioRxiv · Aug 20, 2019Animal Behavior & Cognition