Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress
J. Liang, G. Ruthel, C. Sagum, M. T. Bedford, S. Sidhu, M. Sudol, C. K. Jaladanki, H. Fan, B. Freedman, R. N. Harty
This study identifies WWOX as a host protein that interacts with viral PPxY motifs to inhibit virus egress, revealing a competitive interplay with angiomotin.
bioRxiv · Jan 26, 2021Microbiology