Author

B. Freedman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Organism:bacteria (other)· 1

Frequent Co-Authors

J. Liang· 3 shared R. N. Harty· 3 shared G. Ruthel· 2 shared A. B. Reitz· 1 shared A. Roy· 1 shared A. Shepley-McTaggart· 1 shared A. Whigham· 1 shared C. K. Jaladanki· 1 shared

Activity by Year

2021-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

J. Liang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Enterobacter Sp. SM3 Exhibits Run-and-Tumble Motility

S. G. Johnson, B. Freedman, J. X. Tang

This paper studies the run-and-tumble motility of Enterobacter sp. SM3 in response to chemoattractants, finding similar behavior to E. coli but with distinct responses to serine and aspartate.

bioRxiv · Jul 24, 2023 · PreprintMicrobiology

WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 VLPs

J. Liang, G. Ruthel, B. Freedman, R. N. Harty

This study shows that WWOX interacts with and degrades AMOTp130, reducing its ability to support filovirus VP40 VLP egress.

bioRxiv · Nov 19, 2021Microbiology

Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis.

J. Gopalan, M. Omar, A. Roy, N. M. Cruz, J. Falcone, K. Forbush, J. Himmelfarb, B. Freedman, J. D. Scott

The paper shows that targeting the AKAP220-PPI-HDAC6 pathway restores renal ciliary homeostasis in ADPKD models by modulating actin dynamics and cilia development.

bioRxiv · Feb 24, 2021Cell Biology

Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress

J. Liang, G. Ruthel, C. Sagum, M. T. Bedford, S. Sidhu, M. Sudol, C. K. Jaladanki, H. Fan, B. Freedman, R. N. Harty

This study identifies WWOX as a host protein that interacts with viral PPxY motifs to inhibit virus egress, revealing a competitive interplay with angiomotin.

bioRxiv · Jan 26, 2021Microbiology

Compound FC-10696 Inhibits Egress and Spread of Marburg Virus

Z. Han, H. Ye, J. Liang, A. Shepley-McTaggart, J. E. Wrobel, A. B. Reitz, A. Whigham, K. N. Kavelish, M. S. Saporito, B. Freedman, O. Shtanko, R. N. Harty

The paper identifies FC-10696 as a novel compound that inhibits Marburg virus egress and spread, showing antiviral effects in cell cultures and animal models.

bioRxiv · Jan 15, 2021Microbiology