Heparan Sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE
M. Li, C. Y. Ong, C. J. Langouet-Astrie, L. TAN, A. Verma, Y. Yang, X. Zhang, D. Shah, E. P. Schmidt, D. Xu
This study shows that heparan sulfate-dependent RAGE oligomerization is essential for RAGE signaling and demonstrates a monoclonal antibody that blocks this interaction.
eLife · Feb 9, 2022Peer-reviewedCell Biology