RHAMMB-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment
X. Chen, S. K. Lee, M. Song, T. Zhang, M. S. Han, Y.-T. Chen, Z. Chen, X. Ma, C.-H. Tung, Y.-C. N. Du
This paper develops a RHAMMB-targeting nanoparticle delivering siBcl-xL and KLA peptide to treat PNETs, showing synergistic tumor reduction in mice.
bioRxiv · Feb 28, 2021Cancer Biology