Author

Y.-C. N. Du

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

G. Zhang· 3 shared X. Chen· 3 shared Z. Chen· 3 shared D. Wang· 2 shared T. Zhang· 2 shared Y.-T. Chen· 2 shared A. Lin· 1 shared A. Verma· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

G. Zhang

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4 papers

Recent·Most cited

RHAMMB-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment

X. Chen, S. K. Lee, M. Song, T. Zhang, M. S. Han, Y.-T. Chen, Z. Chen, X. Ma, C.-H. Tung, Y.-C. N. Du

This paper develops a RHAMMB-targeting nanoparticle delivering siBcl-xL and KLA peptide to treat PNETs, showing synergistic tumor reduction in mice.

bioRxiv · Feb 28, 2021Cancer Biology

High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate theprogression of pancreatic cancer

J. Feng, A. Lin, X. Chen, D. Wang, M. Wong, G. Zhang, J. Na, T. Zhang, Z. Chen, Y.-T. Chen, Y.-C. N. Du

bioRxiv · Feb 19, 2021Cancer Biology

Oleocanthal and oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells

L. Goren, G. Zhang, S. Kaushik, P. A. Breslin, Y.-C. N. Du, D. A. Foster

This study shows oleocanthal and oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells, reducing tumor burden and extending lifespan in mice.

bioRxiv · Apr 15, 2019Cancer Biology

Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression

S. Choi, D. Wang, X. Chen, L. H. Tang, A. Verma, Z. Chen, B. J. Kim, L. Selesner, K. Robzyk, G. Zhang, S. Pang, T. Han, C. S. Chan, T. J. Fahey, O. Elemento, Y.-C. N. Du

This study identifies RHAMMB as a key driver of pancreatic tumor metastasis, showing its upregulation in PNETs and correlation with poor patient survival through EGFR signaling.

bioRxiv · Apr 8, 2019Cancer Biology