Author

M. S. Han

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. P. Arruda· 1 shared C.-H. Tung· 1 shared E. Cagampan· 1 shared E. Guney· 1 shared E. Tsaousidou· 1 shared G. Parlakgul· 1 shared G. S. Hotamisligil· 1 shared K. Inouye· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

A. P. Arruda

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2 papers

Recent·Most cited

RHAMMB-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment

X. Chen, S. K. Lee, M. Song, T. Zhang, M. S. Han, Y.-T. Chen, Z. Chen, X. Ma, C.-H. Tung, Y.-C. N. Du

This paper develops a RHAMMB-targeting nanoparticle delivering siBcl-xL and KLA peptide to treat PNETs, showing synergistic tumor reduction in mice.

bioRxiv · Feb 28, 2021Cancer Biology

Aberrant Ca2+ homeostasis in adipocytes links inflammation to metabolic dysregulation in obesity

E. Guney, A. P. Arruda, G. Parlakgul, E. Cagampan, N. Min, Y. Lee, L. Greene, E. Tsaousidou, K. Inouye, M. S. Han, R. J. Davis, G. S. Hotamisligil

This study identifies IP3R over-activation in adipocytes as a key mechanism linking obesity, inflammation, and insulin resistance, suggesting therapeutic targeting of Ca2+ homeostasis.

bioRxiv · Oct 28, 2020Physiology