Plakoglobin and HMGB1 mediate intestinal epithelial cell apoptosis induced by Clostridioides difficile TcdB
Y. Li, W. Xu, Y. Ren, H.-C. Cheung, P. Huang, G. Kaur, C.-J. Kuo, S. P. McDonough, S. L. Fubini, S. M. Lipkin, X. Deng, Y.-F. Chang, L. Huang
This study identifies plakoglobin and HMGB1 as key mediators of TcdB-induced intestinal epithelial cell apoptosis through mitochondrial pathways.
bioRxiv · Jul 2, 2021 · PreprintMicrobiology