Author

Caitlin Overmeyer

University of Kansas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Anita Saraf· 1 shared Arshad Ali NooraniiD· 1 shared Brian D. AckleyiD· 1 shared Hung Nguyen DoiD· 1 shared Justin T. DouglasiD· 1 shared Masato MaesakoiD· 1 shared Michael S. WolfeiD· 1 shared Rui ZhouiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Anita Saraf

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1 paper

Recent·Most cited

Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes

Sujan Devkota, Rui Zhou, Vaishnavi Nagarajan, Masato Maesako, Hung Nguyen Do, Arshad Ali Noorani, Caitlin Overmeyer, Sanjay Bhattarai, Justin T. Douglas, Anita Saraf, Yinglong Miao, Brian D. Ackley, Yigong Shi, Michael S. Wolfe

This study shows that Alzheimer's mutations stabilize harmful enzyme-substrate complexes in gamma-secretase, leading to synaptic loss rather than the released Aβ peptides being the primary cause.

bioRxiv · Sep 8, 2023 · PreprintNeuroscience