Author

Justin T. Douglas

University of KansasORCID 0000-0002-7901-184XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anita Saraf· 1 shared Arianna MaffeiiD· 1 shared Arshad Ali NooraniiD· 1 shared Asma AkhteriD· 1 shared Brian D. AckleyiD· 1 shared Caitlin Overmeyer· 1 shared Donghui ZhuiD· 1 shared Firoz AkhteriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Anita Saraf

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2 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedNov 17, 2025

Amyloid Beta Glycation Induces Neuronal Mitochondrial Dysfunction and Alzheimers Pathogenesis via VDAC1-Dependent mtDNA Efflux

Firoz Akhter, Asma Akhter, Xiongwei Zhu…·Donghui Zhu

This paper shows that glycated amyloid-beta causes mitochondrial dysfunction and Alzheimer's pathology by triggering the cGAS-STING pathway via VDAC1-dependent mtDNA release.

13 citationstop 2%

mousehuman

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NeurosciencebioRxivPreprintSep 8, 2023

Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes

Sujan Devkota, Rui Zhou, Vaishnavi Nagarajan…·Michael S. Wolfe

This study shows that Alzheimer's mutations stabilize harmful enzyme-substrate complexes in gamma-secretase, leading to synaptic loss rather than the released Aβ peptides being the primary cause.

1 citation

C. elegansproteomics

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