Author

Calista A. Cline

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Madigan L. BedardiD· 2 shared Nabarun DasguptaiD· 2 shared Zoé A. McElligottiD· 2 shared Alex R. BrowniD· 1 shared Alexandra C. NowlaniD· 1 shared Bryan L. RothiD· 1 shared Caroline G. Clodfelter· 1 shared Jackson G. MurrayiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

Madigan L. BedardORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Xylazine and fentanyl co-administration delays wound healing in mice

Madigan L. Bedard, Roland F. Seim, Alex R. Brown, Calista A. Cline, Kristen N. Gilley, Luke A. Wykoff, Mitchell Huffstickler, Puja Nakkala, Shannon Rausser, Nabarun Dasgupta, Justin C. Strickland, Leon G. Coleman, Zoé A. McElligott

This study shows that xylazine and fentanyl co-administration in mice delays wound healing, while neither drug alone does so at tested doses.

bioRxiv · Jun 18, 2025 · PreprintPharmacology & Toxicology

Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to naloxone administration

Madigan L. Bedard, Jackson G. Murray, Xi‐Ping Huang, Alexandra C. Nowlan, Sara Y. Conley, Sarah E. Mott, Samuel J. Loyack, Calista A. Cline, Caroline G. Clodfelter, Nabarun Dasgupta, Bryan L. Roth, Zoé A. McElligott

This study shows xylazine acts as a kappa opioid receptor agonist and that naloxone induces withdrawal from xylazine and fentanyl/xylazine combinations, with greater sensitivity in females.

bioRxiv · Sep 8, 2023 · PreprintNeuroscience