Vinculin Y822 phosphorylation regulates cardiomyocyte adhesion dynamics and adherens junction maturation in the heart
Xiaofei Li, Rainy Wortelboer, Yi Song, Sahana Balasubramanian, Callie McLain, Alex Hernandez Manriquez, Joseph Suh, Brenton D. Hoffman, Adam V. Kwiatkowski, Glenn L. Radice
This study shows that vinculin Y822 phosphorylation regulates cardiomyocyte adhesion dynamics and adherens junction maturation, with loss of function leading to cardiac dysfunction later in life.
Journal of Cell Science · Dec 15, 2024Peer-reviewedCell Biology