Michael Susithiran Samuel

This study identifies TPD54 as a regulator of protein trafficking in melanoma, showing its role in disease progression and potential as a therapeutic target.

This paper shows that ROCK2 inhibition reduces ECM remodelling and cell growth while impairing migration and invasion in breast cancer models.

This study shows that actomyosin contractility promotes cardiomyocyte proliferation by increasing Yap nuclear translocation via alpha5 integrin signaling in the postnatal heart.