Author

Callum Dark

The University of Melbourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Louise Y ChengiD· 2 shared Andrew R. JudgeiD· 1 shared Benjamin L. ParkeriD· 1 shared Besaiz J. Sánchez-SáncheziD· 1 shared Brian Marc StrameriD· 1 shared Daniel BakopoulosiD· 1 shared Elizabeth L. ChristieiD· 1 shared Gordon Stuart LynchiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Louise Y ChengORCID

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2 papers

Recent·Most cited

Convergent Insulin and TGF-β signalling drives cancer cachexia by promoting aberrant fatbody ECM accumulation in a Drosophila tumour model

Daniel Bakopoulos, Sofya Golenkina, Callum Dark, Elizabeth L. Christie, Besaiz J. Sánchez-Sánchez, Brian Marc Stramer, Louise Y Cheng

This study identifies insulin and TGF-β signaling convergence in Drosophila adipose tissue that drives ECM accumulation and muscle wasting in a tumor model.

EMBO Reports · Nov 28, 2023Peer-reviewedDevelopmental Biology

Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model

Callum Dark, Nashia Ali, Sofia Golenkina, Ronnie Blazev, Benjamin L. Parker, Katherine Murphy, Gordon Stuart Lynch, Tarosi Senapati, S. Sean Millard, Sarah M. Judge, Andrew R. Judge, Louise Y Cheng

This study identifies mitochondrial fusion and beta-oxidation as key drivers of muscle wasting in a Drosophila cancer cachexia model and shows interventions can mitigate muscle loss.

bioRxiv · Jun 23, 2023 · PreprintDevelopmental Biology