Convergent Insulin and TGF-β signalling drives cancer cachexia by promoting aberrant fatbody ECM accumulation in a Drosophila tumour model
Daniel Bakopoulos, Sofya Golenkina, Callum Dark…·Louise Y Cheng
This study identifies insulin and TGF-β signaling convergence in Drosophila adipose tissue that drives ECM accumulation and muscle wasting in a tumor model.