Brian Marc Stramer

This study uses scRNA-seq to compare fibroblast subtypes in keloid and normal skin tissues with cultured fibroblasts, finding that some disease-associated features persist in vitro.

This study develops and simulates a computational model to understand how cell properties affect collective alignment, finding optimal self-propulsion and overlap avoidance ratios, and the role of deformability and junctions.

This study identifies insulin and TGF-β signaling convergence in Drosophila adipose tissue that drives ECM accumulation and muscle wasting in a tumor model.

GliaMorph quantifies Müller glial cell morphology across developmental and disease states, revealing structural changes and subcellular features in zebrafish and mouse models.

This study shows that extracellular matrix assembly stress actively drives morphogenesis in Drosophila ventral nerve cord by generating surface tension during collagen-IV network formation.