Checkpoint non-fidelity induces a complex landscape of lineage fitness after DNA damage
Callum J. Campbell, Ashok R. Venkitaraman, Alessandro Esposito
The paper shows that transient DNA damage with checkpoint non-fidelity leads to varied lineage fitness outcomes in descendant cells, promoting persistence in mutagenic environments.
bioRxiv · Oct 2, 2018 · PreprintCancer Biology