Ccp1 depletion disrupts network integration of hippocampal parvalbumin interneurons
Romain Le Bail, Bernard Lakaye, Ira Espuny-Camacho, Carsten Janke, Maria M. Magiera, Dominique Engel, Carla Silva, Laurent Nguyen
This study shows that Ccp1 depletion in hippocampal parvalbumin interneurons leads to hyperglutamylation, impaired axonal transport, and reduced perisomatic inhibition of pyramidal cells in the CA2 region.
iScience · Sep 1, 2025Peer-reviewedNeuroscience