Maria M. Magiera

This study shows that reduced microtubule polyglutamylation causes neuronal dysfunction and worsens Tau-induced neurodegeneration in mice.

This study shows that loss of tubulin tyrosination in Purkinje neurons does not lead to their degeneration, unlike polyglutamylation dysregulation.

The paper investigates Eml1 mutations in mice, finding altered organelle distribution and translation defects in radial glia cells, contributing to subcortical heterotopia.

The paper shows Trim69 remodels microtubules to inhibit HIV virion core migration by stalling dynein/dynactin complexes.

This study shows that Ccp1 depletion in hippocampal parvalbumin interneurons leads to hyperglutamylation, impaired axonal transport, and reduced perisomatic inhibition of pyramidal cells in the CA2 region.

The paper shows that polyglutamylation of microtubules regulates neuronal remodeling by marking them for severing, affecting synapse and axon pruning in both peripheral and central circuits.

This study shows that glutamylation imbalance in photoreceptor cells leads to structural defects and degeneration, highlighting its role in maintaining outer segment architecture.

The paper shows that choroid plexus cilia undergo axoneme resorption through microtubule destabilization, controlled by polyglutamylation and spastin, and is conserved in human samples.

The paper shows that tubulin polyglutamylation regulates microtubule-severing enzymes in axon guidance, with TTLL6 and TTLL11 having distinct roles in zebrafish and mammalian neurons.

This study shows that ATAT1-enriched vesicles are transported along axons to acetylate -tubulin, essential for proper vesicular transport.