Author

Carlin J. Hamill

University of St Andrews

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alison L. DicksoniD· 1 shared Clarissa Melo CzeksteriD· 1 shared David James HarrisoniD· 1 shared Greice Michele ZickuhriD· 1 shared Ramasubramanian SundaramoorthyiD· 1 shared Sally L. ShirraniD· 1 shared Silvia Synowksy· 1 shared Thư Ngọc-Anh TrịnhiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Alison L. DicksonORCID

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Author profile →

1 paper

Recent·Most cited

Dimerization and Threonine-Dependent Stabilization Govern Human YRDC Catalysis

Thư Ngọc-Anh Trịnh, Greice Michele Zickuhr, Alison L. Dickson, Silvia Synowksy, Sally L. Shirran, Carlin J. Hamill, Ramasubramanian Sundaramoorthy, Tomáš Lébl, David James Harrison, Clarissa Melo Czekster

This study elucidates the mechanism of YRDC catalysis, showing that threonine stabilizes the enzyme and dimerization is critical for function, with disease-linked mutations disrupting these processes.

bioRxiv · Jul 31, 2026 · PreprintBiochemistry